添加时间: 2015-06-19 10:33:53 点击次数:
Takao Watanabe, Hiroyuki Kusuhara, Tomoko Watanabe, Yasuyuki Debori, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Brian W. Ogilvie, Andrew Parkinson, Zhuohan Hu and Yuichi Sugiyama
Prediction of the overall renal tubular secretion and hepatic clearance of anionic drugs and a renal drug-drug interaction involving OAT3 in humans by in vitro uptake experiments. Drug Metab. Dispos.2011,39: 1031-1038.
Watanabe,T., Kusuhara,H., Maeda,K., Kanamaru,H., Saito,Y., Hu,Z. and Sugiyama,Y.
Investigation of the rate-determining process in the hepatic elimination of HMG-CoA reductase inhibitors in rats and humans. Drug Metab. Dispos. 2010, 38, 215-222
Wakaba Yamashiro, Kazuya Maeda, Masakazu Hirouchi, Yasuhisa Adachi, Zhuohan Hu,and Yuichi Sugiyama
Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist II AT-receptor, in humans. Drug Metab. Dispos. 2006, 37, 1247 - 1254
Yoshimichi Sai1, Yukio Kato1, Keiko Nakamura1, Sayaka Kato1, Tomohiro Nishimura1, Yoshiyuki Kubo1, Ikumi Tamai2, Shu Yang3, Zhuohan Hu3, Ichimaro Yamada4 and Akira Tsuji.
Carrier-mediated hepatic uptake of a novel non-renal excretion type uric acid generation inhibitor, Y-700. Journal of Pharmacology Science .2006, (95): 236
U.S. Department of Health and Human Services Food and Drug Administration
Center for Drug Evaluation and Research (CDER)
In Vitro Drug Interaction Studies —Cytochrome P450 Enzyme- and Transporter-Mediated Drug Interactions Guidance for Industry(January 2020 Clinical Pharmacology)
Shujun Fu , Feifei Yu , Tao Sun , Zhuohan Hu
Transporter-mediated drug–drug interactions – Study design, data analysis,and implications for in vitro evaluations
Shujun Fu , Feifei Yu , Zhuohan Hu Tao Sun
Metabolism-mediated drug–drug interactions – Study design, data analysis, and implications for in vitro evaluations
Bent H. Hellum, Zhuohan Hu, Odd Georg Nilsen
The Induction of CYP1A2, CYP2D6 and CYP3A4 by Six Trade Herbal Products in Cultured Primary Human Hepatocytes. Basic & Clinical Pharmacology & Toxicology. 2007, 100: 23-30